Discovery of Native Autoantigens via Antigen Surrogate Technology: Application to Type 1 Diabetes
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چکیده
منابع مشابه
Discovery of Native Autoantigens via Antigen Surrogate Technology: Application to Type 1 Diabetes
A fundamental goal in understanding the mechanisms of autoimmune disease is the characterization of autoantigens that are targeted by autoreactive antibodies and T cells. Unfortunately, the identification of autoantigens is a difficult problem. We have begun to explore a novel route to the discovery of autoantibody/autoantigen pairs that involves comparative screening of combinatorial libraries...
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ژورنال
عنوان ژورنال: ACS Chemical Biology
سال: 2014
ISSN: 1554-8929,1554-8937
DOI: 10.1021/cb5007618